Baja PEEP protocolo utilizado en los estudios ARMA, FACTT, Omega, EDEN, SAILS, y ALVEOLI | ||||||||
FiO2 | 0'3 | 0'4 | 0'5 | 0'6 | 0'7 | 0'8 | 0'9 | 1 |
PEEP | 5 | 5-8 | 8-10 | 10 | 10-14 | 14 | 14-18 | 18-24 |
Alta PEEP protocolo utilizado en el studio ALVEOLI | ||||||||
FiO2 | 0'3 | 0'4 | 0'5 | 0'6 | 0'7 | 0'8 | 0'9 | 1 |
PEEP | 12-14 | 14-16 | 16-18 | 20 | 20 | 22 | 22 | 22-24 |
Referencia: Higher versus Lower Positive End-Expiratory Pressures in Patients with the Acute Respiratory Distress Syndrome
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The National Heart, Lung, and Blood Institute ARDS Clinical Trials Network
"...These results suggest that in patients with acute lung injury and ARDS who receive mechanical ventilation with a tidal-volume goal of 6 ml per kilogram of predicted body weight and an end-inspiratory plateau-pressure limit of 30 cm of water, clinical outcomes are similar whether lower or higher PEEP levels are used."