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PEEP en el SDRA

Protocolo de baja y alta PEEP utilizados en difrentes estudios

Baja PEEP protocolo utilizado en los estudios ARMA, FACTT, Omega, EDEN, SAILS, y ALVEOLI
FiO2 0'30'40'50'60'70'80'91
PEEP 55-88-101010-141414-1818-24
Alta PEEP protocolo utilizado en el studio ALVEOLI
FiO2 0'30'40'50'60'70'80'91
PEEP 12-1414-1616-182020222222-24

Referencia: Higher versus Lower Positive End-Expiratory Pressures in Patients with the Acute Respiratory Distress Syndrome . The National Heart, Lung, and Blood Institute ARDS Clinical Trials Network
"...These results suggest that in patients with acute lung injury and ARDS who receive mechanical ventilation with a tidal-volume goal of 6 ml per kilogram of predicted body weight and an end-inspiratory plateau-pressure limit of 30 cm of water, clinical outcomes are similar whether lower or higher PEEP levels are used."